27-Sep-2022 | Facts and Factors
According to Facts and Factors, the global hirudin market size was worth around USD 3908.9 million in 2021 and is predicted to grow to around USD 4575.60 million by 2028 with a compound annual growth rate (CAGR) of roughly 2.7% between 2022 and 2028.
Hirudin is a peptide found in the salivary glands of Hirudo medicinalis and possesses properties that can prevent blood coagulation. Hirudin is used extensively in the pharmaceutical sector since it has wide applications in the production of anticoagulants that are used to prevent blood clots from occurring due to various medical conditions. A full length is made of 65 amino acids that are organized in a small N-terminal domain with 3 disulfide bonds as well as a C-terminal domain that exists without any order when the protein loses its complexity in a solution. Hirudin is considered one of the most potential thrombin inhibitors however, in contrast to antithrombin, hirudin acts only on activated thrombin resulting in the prevention or dissolution of thrombi or clots. It has also found uses in the treatment of skin hematomas, which refers to localized bleeding outside blood vessels.
Browse the full “Hirudin Market Size, Share, Growth Analysis Report By Application (Cerebral Thrombosis, Myocardial Thrombosis, Skin Hematomas, Stroke, Deep Vein Thrombosis, and Application Cream), By Type (Recombinant Hirudin, and Natural Hirudin), and By Region - Global and Regional Industry Insights, Overview, Comprehensive Analysis, Trends, Statistical Research, Market Intelligence, Historical Data and Forecast 2022 – 2028" report at https://www.fnfresearch.com/hirudin-market
Since natural hirudin is difficult to be extracted in natural ways, recombinant hirudins are currently used extensively. Direct thrombin inhibitors are also derived with the aid of hirudin using chemical processes.
During Covid-19, the demand for the hirudin increased by high margins driving the global market demand. Since pharmaceutical and healthcare segments were amongst the only few industries that were completely operational during the pandemic since they qualified as essential segments, the operation in these sectors remained unaffected. In fact, demand for certain medical products increased considerably, anticoagulants being one of them.
The global hirudin market is projected to grow owing to the increasing cases of cardiovascular diseases (CVDs). Since stroke and other CVDs have become extremely common in the current world, pharmaceutical companies along with the healthcare sector are working toward developing as many assistive medical treatments as possible further driving the demand for hirudin. Varicose veins are another form of a medical condition that has a high prevalence. The disease causes superficial veins to become twisted and enlarged causing some patients to develop pain in the affected area, which is generally the legs section. As per official records, varicose veins are extremely common and affect 3 in every 10 adults, with the female population being more prone to the condition than the male population. Since hirudin can be used to effectively treat the condition, it has high demand in the healthcare segment. Skin hematomas, which generally occur due to other diseases, or if a person has undergone surgery, injury, or trauma, can be treated with the help of hirudin-derived products owing to their anticoagulation properties. The increasing number of patients suffering from skin hematomas may also contribute to the global market size growth trend.
The difficulty in extracting large amounts of natural hirudin may restrict the global market expansion while the growing use of desirudin is expected to provide excellent expansion opportunities along with challenges owing to issues concerning the use amongst patients with renal dysfunction.
The global hirudin market is segmented based on type, application, and region.
Based on type, the global market is divided into recombinant hirudin and natural hirudin. The global market generated the highest revenue from the recombinant hirudin segment owing to the difficulty in procuring the anticoagulant from its natural state. As per Statista, the United States government spent around USD 7.7 billion on the development of biotechnology, which is projected to grow even further in the coming years as the demand for more bio-research grows.
Based on application, the global market segments are cerebral thrombosis, myocardial thrombosis, skin hematomas, deep vein thrombosis, stroke, and application cream. The global market is dominated by the deep vein thrombosis segment, which refers to the formation of a blood clot in a single or multiple bodily deep veins, mostly concentrated in the legs. As per research, around 33% of the people diagnosed with deep thrombosis are known to suffer from long-term complications like pain, swelling, scaling, or discoloration of the infected area.
North America is projected to dominate the global hirudin market driven by the increasing number of United States Food & Drug Administration (US FDA) approvals witnessed in the pharmaceutical sector. The US is home to one of the large pharmaceutical industries which are home to some of the world’s leading giants. For instance, Pfizer, the world’s top pharma giant, is headquartered in Connecticut, America. The company has increased investment in its research & development wing, especially after the pandemic. For instance, as per Macrotrends, the company spent over USD 13, 829 billion on R & D in 2021, which was an increase of 47.23% from its research investment in 2020. Asia-Pacific may also generate high revenue owing to the growing interest of the international domestic toward the economies of India and China, which have true growth potential in the medical sector.
Report Scope
Report Attribute |
Details |
Market Size in 2021 |
USD 3908.9 Million |
Projected Market Size in 2028 |
USD 4575.60 Million |
CAGR Growth Rate |
2.7% CAGR |
Base Year |
2021 |
Forecast Years |
2022-2028 |
Key Market Players |
Bristol-Myers Squibb Company, Bayer Healthcare AG, GlaxoSmithKline Plc., Aspen Holdings, Teva Pharmaceutical Industries Ltd., Pfizer Inc., and others. |
Key Segment |
By Application, Type, and Region |
Major Regions Covered |
North America, Europe, Asia Pacific, Latin America, and the Middle East &, Africa |
Purchase Options |
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The global hirudin market is led by players including Bristol-Myers Squibb Company, Bayer Healthcare AG, GlaxoSmithKline Plc., Aspen Holdings, Teva Pharmaceutical Industries Ltd., and Pfizer, Inc.
Recent Developments:
- In December 2019, LUNAC Therapeutics, a UK-based company focusing on drug discovery, announced that it has received funding of £3.14 million to aid the company’s work on identifying and developing advanced anticoagulants.
- In July 2020, VarmX raised €32 million in investment toward the company's work on the anticoagulation reversal.
The global hirudin market is segmented as follows:
By Application
- Cerebral Thrombosis
- Myocardial Thrombosis
- Skin Hematomas
- Stroke
- Deep Vein Thrombosis
- Application Cream
By Type
- Recombinant Hirudin
- Natural Hirudin
By Region
- North America
- Europe
- France
- The UK
- Spain
- Germany
- Italy
- Nordic Countries
- Benelux Union
- Belgium
- The Netherlands
- Luxembourg
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Australia
- South Korea
- Southeast Asia
- Indonesia
- Thailand
- Malaysia
- Singapore
- Rest of Southeast Asia
- Rest of Asia Pacific
- The Middle East & Africa
- Saudi Arabia
- UAE
- Egypt
- South Africa
- Rest of the Middle East & Africa
- Latin America
- Brazil
- Argentina
- Rest of Latin America
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