Chiral Chromatography Column Market Size, Share Global Analysis Report, 2022 – 2028

Industry Insights

[215+ Pages Report] According to the report published by Facts Factors, the global chiral chromatography column market size was worth USD 69.40 million in 2021 and is estimated to grow to USD 97.88 million by 2028, with a compound annual growth rate (CAGR) of approximately 5.90% over the forecast period. The report analyzes the chiral chromatography column market’s drivers, restraints/challenges, and their effect on the demands during the projection period. In addition, the report explores emerging opportunities in the chiral chromatography column market.

Market Overview

High-performance liquid chromatography separation using chiral chromatography is used to separate isomers. It is a single enantiomer of a chiral molecule rather than being achiral in the stationary process. The two enantiomers of the same analytical material respond differently to the stationary single enantiomer step, which causes them to depart from the board at separate periods. The stationary phase in chiral column chromatography contains one enantiomer of a chiral material. The chiral stationary phase in this chromatography is made of silica gel, achiral support, and chiral chemical. Increased chromatography applications in pharmaceutical & biopharmaceutical industries and rising R&D investments by pharmaceutical & biotechnology organizations are the main market drivers for chiral chromatography columns. However, throughout the projected period, the market expansion is anticipated to be constrained by high reagent costs and a lack of qualified professionals.

COVID-19 Impact:

The COVID-19 pandemic has increased pressure on pharma and clinical labs while stepping up drug discovery and research activities. The COVID-19 pandemic continues to alter the development of numerous businesses, but its immediate effects are still varied. While some industries may see a decline in demand, others will remain stable and provide bright prospects for expansion need for chiral chromatography columns has increased over time. Still, due to the unanticipated COVID-19 epidemic, the industry is anticipated to increase even more in 2020 as more chromatography techniques are used to approve different medications.

Key Insights

• As per the analysis shared by our research analyst, the global chiral chromatography column market value is expected to grow at a CAGR of 5.90% over the forecast period.
• In terms of revenue, the global chiral chromatography column market size was valued at around USD 69.40 million in 2021 and is projected to reach USD 97.88 million by 2028.
• Increased chromatography applications in pharmaceutical & biopharmaceutical industries and rising R&D investments by pharmaceutical and biotechnology organizations are the main market drivers for chiral chromatography columns.
• By product type, the prepacked column category dominated the market in 2021.
• By end-user, the pharmaceutical and biotechnology companies dominated the market in 2021.
• North America dominated the chiral chromatography column market in 2021.

Growth Drivers

• The rising application of chiral chromatography columns in biotechnology and pharmaceutical sectors drives the market growth

The global chiral chromatography column market is expanding due to its applications in pharmaceutical, biotechnology, and other industries. The pharmaceutical and biotechnology companies have been urged to employ the cutting-edge chromatographic approach that drives market expansion by increased government spending, funding, and subsidies. A key factor in moving the chiral chromatography columns market to the next level are advancements in chiral chromatography columns and their technology. Other factors include the growing importance of chromatography studies in approving drugs and heavy investment in research and development by life science firms.

Restraints

• High cost of chromatography equipment likely to hamper the market growth

Factors limiting the global chiral chromatography column market expansion include the high cost of chromatography equipment and the need for experienced specialists to operate pricey chromatography equipment.

Segmentation Analysis

The global chiral chromatography column market is segregated based on product type, material type, technology, and end-user.

Based on type, the market is divided into prepacked columns and empty columns. Among these, the prepacked column segment led the market in 2021 and is expected to maintain its dominance throughout the forecast period. Prepacked columns are consistent and have few deviations. Early method development for improving column packing makes use of these columns. Due to their capacity to run several samples daily, these columns are frequently utilized in industries. As a result, prepacked columns rule the market for chiral chromatography columns.

Based on material type, the market is divided into metal-based, glass-based, and plastic-based. Among these, the metal-based segment led the market in 2021 and is expected to maintain its dominance throughout the forecast period. Chiral surfaces play a crucial role in preparing enantiomerically pure drugs and other enantioselective heterogeneous procedures. Metal-based columns provide better tensile strength and suitability for high flow rate processes.

Based on technology, the market is classified into liquid chromatography (LC), gas chromatography (GC), supercritical fluid chromatography (SFC), thin layer chromatography, flash chromatography, and other technologies (other technologies include paper chromatography). Among these, the liquid chromatography segment led the market in 2021 and is expected to maintain its dominance throughout the forecast period. When using liquid chromatography, the solvents are in the mobile phase. In analytical laboratories, the identification and measurement of food components, medicines, and other bioactive substances are widely used. The HPLC analytical reagents are crucial for both lengthening and shortening retention times.

Based on end-user, the market is classified into pharmaceutical & biotechnology companies, academic institutes, food & beverage manufacturers, hospital & diagnostic clinics, environmental testing laboratories, cosmeceutical companies, and nutraceutical companies. The pharmaceutical and biotechnology companies dominated the market in 2021. Pharmaceutical businesses manufacture vast volumes of exceedingly pure materials using chromatography, then check the substances for traces of impurities. Chromatography is increasingly being used in the pharmaceutical sector to separate chiral substances. Some of the uses of chiral chromatography in biotechnology include separating particular proteins, amino acids, or other macromolecules from a sample. In this industry, evaluating the yield, price, and purity of goods like inulin, growth hormone, interferons, erythropoietin, and others is critical.

Recent Developments

• January 2021: Thermo Fisher and Astrea Bioseparations signed a contract to provide EvolveD columns containing exclusive CaptureSelect and POROS chromatography resins by Astrea. To create biotherapeutics, molecules are purified using columns and resins.

Report Scope

Regional Landscape

• North America dominated the chiral chromatography column market in 2021

In 2021, the global chiral chromatography columns market was dominated by North America. Numerous factors contribute to this, foremost among them the growth of the worldwide biotechnology and pharmaceutical industries. The United States now holds the largest market share in the North American region due to many factors, including new advancements, a steep rise in unique product releases, and a rising number of conferences devoted to chromatography. The market is expanding due to the quickly growing manufacturing industry, expanding manufacturing businesses, and increasing the number of academic institutions.

Competitive Landscape

• Agilent Technologies 
• Thermo Fisher Scientific 
• Waters Corporation 
• Daicel Corporation 
• Bio-Rad Laboratories 
• W.R.Grace & Co. 
• Merk Group 
• GL Sciencies 
• Perkin Elmer 
• Shimadzu Corporation 
• Sartorious Group 
• Cytiva 
• ES Industries 
• Phenomenex. 

Chiral Chromatography Column Market is segmented as follows:

By Product Type

• Prepacked column
• Empty column

By Material Type

• Metal-based
• Glass based
• Plastic-based

By Technology

• Liquid chromatography (LC)
• Gas chromatography (GC)
• Supercritical fluid chromatography (SFC)
• Thin layer chromatography
• Flash chromatography
• Other technologies (other technologies include paper chromatography)

By End-User

• Pharmaceutical biotechnology companies
• Academic institutes
• Food & beverage manufacturers
• Hospital & diagnostic clinics
• Environmental testing laboratories
• Cosmeceutical companies
• Nutraceutical companies

By Regional Segment Analysis

• North America
  • The U.S.
  • Canada
  • Mexico
• Europe
  • France
  • The UK
  • Spain
  • Germany
  • Italy
  • Nordic Countries
    • Denmark
    • Sweden
    • Norway
  • Benelux Union
    • Belgium
    • The Netherlands
    • Luxembourg
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • Australia
  • South Korea
  • Southeast Asia
    • Indonesia
    • Thailand
    • Malaysia
    • Singapore
    • Rest of Southeast Asia
  • Rest of Asia Pacific
• The Middle East & Africa
  • Saudi Arabia
  • UAE
  • Egypt
  • South Africa
  • Rest of the Middle East & Africa
• Latin America
  • Brazil
  • Argentina
  • Rest of Latin America